Pregnancy and the birth of a healthy child is the goal of the IVF procedure.
Most human embryos do not implant or are aborted.
Naturally, a fertile couple gets pregnant after 5-6 months of trying. Out of 100 couples, 20 get pregnant in the first month, the success rate being 20%.
In IVF, the success rate is similarly calculated for one month (one IVF cycle).
Pregnancy rate is the percentage of couples who get pregnant in an IVF cycle.
There are several ways to report the success rate:
- Success rate on embryo transfer – the percentage of pregnancies after an embryo transfer
- Success rate on an IVF cycle – after the transfer of all embryos, including frozen ones
- Patient success rate – the percentage of patients who get pregnant, from several procedures
Interpretation can create a lot of confusion if the calculation method is not specified or if figures from different categories are compared.
Factors with major impact:
- Woman’s age (most significant factor)
- Number of oocytes collected
Other factors that influence success rates:
- Sperm quality
- Partners’ lifestyle (smoking, obesity)
- Certain associated medical problems
- Cultivation conditions in the IVF laboratory
- Team skills and experience
Many of the collected oocytes have defects (accumulated over time) and produce abnormal embryos.
Most formed embryos have either an abnormal number of chromosomes (aneuploid embryos) or insufficient resources to evolve.
The percentage of abnormal embryos increases significantly with age.
The IVF procedure does not improve the embryos, but only selects those with chances of implantation.
Success rates exceed 50% under the age of 35, but the percentage drops below 10% after the age of 40.
We are proud of the remarkable results obtained and especially of most IVF children in the country.
The average success rate in Europe has been constant in recent years, around 35% of clinical pregnancies on embryo transfer. With frozen embryos, the chances of success were close.
In the Gynera Clinic, the annual average was constantly over 45%, and in the case of frozen embryos it is, in recent years, over 50%.
But these are average chances. For each, the most important thing is what personalized chances of success it has, depending on age and ovarian reserve of oocytes.
The analysis of over 4000 IVF procedures performed in the Gynera Clinic allowed the calculation with high statistical probability of the real chances of success of our patients. However, these data are not valid for other clinics, in other conditions and with another team of specialists.