IVF with donated oocytes

IVF with donated oocytes

In vitro fertilization with donated oocytes is recommended when infertility is determined by the quality of the oocytes or their low reserve.

The most common indications are:

  • Age over 43-44 years
  • Very low oocyte reserve
  • Menopause
  • Repeated IVF failures with own oocytes, attributed to embryo quality
  • Communicable genetic diseases
What options are there?

IVF in a clinic abroad * that can provide a compatible anonymous donor

  • The IVF procedure is performed abroad, in the clinic chosen by the patients
  • Preparatory services and treatment monitoring can be provided in the country
  • Clinics abroad may have different work protocols, requirements, costs and outcomes.

IVF in the Gynera Clinic with frozen oocytes, imported from an oocyte bank

What is the chance of success for IVF with donated oocytes?

The chance of implanting an embryo in an advanced stage of evolution (blastocyst) obtained with an oocyte from a young donor is over 35-40%. As at least 2 quality embryos are usually obtained from a donation, the total chance of success of the procedure is over 60-65%. If 2 blastocysts are obtained, it is recommended to perform embryo transfer with a single embryo, in order to reduce the risk of twin pregnancy. The second embryo can be frozen, stored for a variable period and then used for embryo transfer.

Can I choose the donor profile?

Most clinics choose the profile of the donor to match that of the receiving couple, after completing a questionnaire. In addition, the couple may require certain characteristics for the donor: blood type, Rh, race, hair or eye color. Sometimes specific genetic tests may be required for at-risk couples.

What do we need to do to access the IVF Program with donated oocytes?

Contact the clinic to make an appointment. During the consultation you will benefit from a medical evaluation, personalized recommendations and additional details.

Can I get IVF with oocytes donated by a known donor?

The IVF procedure with known donor involves the existence of a known person or relative who wants to donate oocytes voluntarily and free of charge, in order to help the receiving couple.

A donor must meet certain requirements in order to be able to make a donation and agree to investigate, perform all legal steps, ovarian stimulation and oocyte sampling by puncture.

What is the minimum number of donated oocytes received in an IVF procedure?

Oocyte banks recommend packs of 7-8 frozen oocytes, in order to obtain 2 blastocysts.

Some clinics abroad guarantee a minimum of 6 donated oocytes. If this minimum number of oocytes is not collected, there may be financial facilities for a new procedure.

What is the mother's contribution to the child's development if donated oocytes are used?

Recent studies show that the period of intrauterine training has a stronger influence on the health, skills and general development of the child than genetic predispositions. The transmitted genetic material can be combined between partners in various variants, and then the genes are programmed to become active or inactive under the action of external factors, especially intrauterine, when the embryo is sensitive, being formed. Some predominantly genetic traits are taken into account when choosing a donor. For the others, the contribution of the period of pregnancy, birth and breastfeeding to the development of the future child is more important than the genetic profile of the reproductive cells. The emotional connection established between mother and fetus during pregnancy is also invaluable.

What is the minimum set of investigations required?
  • Lady: Pap smear, TSH, Prolactin, genital and breast ultrasound
  • Sir: Spermogram
  • Both partners: HBs Ag, HBc Ac, HCV, HIV, VDRL / TPHA, Blood group, Rh
What is the treatment for IVF with donated oocytes?

The oocyte recipient can make the embryo transfer in a natural cycle, without treatment, if she ovulates regularly.

In most cases, an artificial cycle is recommended, which can be controlled with medication. It consists of the administration of estrogen and progesterone in doses that mimic the natural cycle and prepare the uterus for implantation. The treatment is maintained in the first three months of pregnancy.